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97,98 Parks team demonstrated that saponin extract exposure dramatically decreased miR-21-5p expression in HESCs and upregulated caspase-3 expression, which in turn promoted cell apoptosis

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Ethics statement This study included experimental procedures were approved by the institutional animal care and use committee of The First Affiliated Hospital of Wenzhou Medical University (wydw2015-0096) and the National Institutes of Health Guide for Care and Use of Laboratory Animals

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R., Arden, N., Berenbaum, F., Blanco, F